Proteins

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A service for biological sequence analysis, consisting of 2884 blocks representing 770 protein groups. Blocks are multiply aligned ungapped segments corresponding to the most highly conserved regions of proteins. Block Searcher, Get Blocks and Block Maker are aids to detection and verification of protein sequence homology. They compare a protein or DNA sequence to a database of protein blocks, retrieve blocks, and create new blocks, respectively.
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Twice monthly periodical devoted to publishing research on genetics and molecular biology, structure and function, enzymes and proteins, physiology and metabolism, cell surfaces, plant microbiology, plasmids and transposons, bacteriophages, eukaryotic cells, population genetics, and evolution.
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An interactive database of mouse kidney protein. Includes search options such as protein name, keyword or by listing all known proteins.
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Summary of the current consensus and evidence about bovine spongiform encephalopathy (BSE), CJD, and the prion hypothesis.
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Document describing infectious agents which do not have a nucleic acid genome. They are called prions, which are defined as 'small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids'. Examples of prion diseases are scrapie, tme, cwd, bse, and cjd.
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Computer visualisations of viruses, topographical maps, interactive visualisations of viruses, and protein data bank files.
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Article considering how bovine prions may have been passed to humans, resulting in a new form of CJD. Prions are transmissible particles that are devoid of nucleic acid and seem to be composed exclusively of a modified protein. BSE and human CJD are among the most notable central nervous system degenerative disorders caused by prions.
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A collection of information about restriction enzymes, methylases, and the microorganisms from which they have been isolated - isoschizomers, recognition sequences, cleavage sites, methylation specificity, commercial availability and a bibliography.
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International science education course. Graphical and hypertext material for the course has been supplied by 30 experts in protein structure, many of whom also contribute to email discussions and tutorials. Winner of the 1996 UCISA award for promoting good practice in the use of the Web within the UK higher education sector.
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An extensive, annotated and non-redundant set of protein sequence databases in which over 115,000 entries are classified into family groups and alignments of each group are available.
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Electronic and Internet-accessible tools and resources for molecular biology, biotechnology, molecular evolution, genetics, biochemistry and biomolecular modelling. Includes links to protein and DNA data analysis servers which provide sequence and structural homology searches etc.
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Set of links to journals relevant to biochemistry, biophysics, cell biology and molecular biology. Some have only subscription information online, others have tables of contents, abstracts or full text.
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A guide to predicting protein 3D structure. Headings include sequence database searching, domain assignment, multiple sequence alignment, comparative or homology modelling, secondary structure prediction, fold recognition, analysis of fold families and alignment of secondary structures.
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The EMBO Journal provides for rapid publication of full length papers describing original research of general rather than specialist interest in molecular biology and related areas. The journal selects those manuscripts which merit urgent publication because they report novel findings of wide biological significance.
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Collection of labelled diagrams illustrating key processes of biotechnology for the purposes of biology teaching and learning. Includes diagrams and explanations of the structure of DNA, DNA replication, protein synthesis, control of gene expression, chemical bonds, plant cells, chromosome mutation, meiosis, mitosis, recessive and dominant inheritance, viruses and cell processes.
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SWISS-PROT and its supplement TrEMBL are curated protein sequence databases which aim to complement other such databases. Information available includes the function and structure of a protein, its post-translational modifications and variants.
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Database showing the molecular structures of enzymes deposited in the Brookhaven Protein Data Bank (PDB). Entries are organised, and can be browsed, by their enzyme classification numbers.
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Server dedicated to the analysis of protein sequences and structures, as well as 2-D PAGE.
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Service offering remote protein sequence analysis. There is a choice of sequence analysis mthods (Prosite, Fasta), secondary structure prediction and databases for pattern search.
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Software directory related to molecular biology and genetics. Domains include DNA, protein, molecular evolution and databases.
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